Cholesterol Desmolase

《英文msh詞典》Cholesterol Desmolase
[同義詞] Cholesterol Desmolase
[主題詞] Cholesterol Side-Chain Cleavage Enzyme
[中文釋義] 膽固醇碳鏈酶
[英文釋義] A mitochondrial cytochrome P450 enzyme that catalyzes the side-chain cleavage of C27 CHOLESTEROL to C21 PREGNENOLONE in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme,encoded by CYP11A1 gene,catalyzes the breakage between C20 and C22 which is the initial and rate-limiting step in the biosynthesis of various gonadal and adrenal steroid hormones.